Protein Details: Chloride channel protein CLC-f

Protein ID

ICDB_Pro_1309

Protein Name

Chloride channel protein CLC-f

Gene Name

CLC-F; CBSCLC1; At1g55620; F20N2.5

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

781 amino acids

AlphaFoldDB

AF-Q8RXR2-F1-model_v4.pdb

Function

Voltage-gated chloride channel.

Sequence

MSSGGAGEYNEDRHLLRSTDGDEVGIGGGEGDLDVESQSPAIRSGAGGVRDLFKHIDRRFSLSGRRLSFKRMENIRVDRERHNPSSSSAFSAAGEEDGGGISNLHSVDDRNDEYGFDEEVLGDSAPPEWALLLIGCLIGVAAGICVAGFNKGVHVIHEWAWAGTPNEGAAWLRLQRLADTWHRILLIPVTGGVIVGMMHGLLEILDQIRQSNSSQRQGLDFLAGIYPVIKAIQAAVTLGTGCSLGPEGPSVDIGKSCANGFALMMENNRERRIALTAAGAASGIASGFNAAVAGCFFAIETVLRPLRAENSPPFTTAMIILASVISSTVSNALLGTQSAFTVPSYDLKSAAELPLYLILGMLCGAVSVVFSRLVTWFTKSFDFIKDKFGLPAIVCPALGGLGAGIIALKYPGILYWGFTNVEEILHTGKSASAPGIWLLAQLAAAKVVATALCKGSGLVGGLYAPSLMIGAAVGAVFGGSAAEIINRAIPGNAAVAQPQAYALVGMAATLASMCSVPLTSVLLLFELTKDYRILLPLMGAVGLAIWVPSVANQGKESDSSEGRSTGRGYSSLSPSERKTEGVWRHTDNADSLELTVIENPDHNSFLDEETILEDLKVMRVMSKNYVKVSSGTTLREARNILKESHQNCIMVVDDDDFLAGILTHGDIRRYLSNNASTILDENTCPVSSVCTKKISYRGQERGLLTCYPDATVGVAKELMEARGVKQLPVVKRGEVIHKGKRRKLLGLLHYDSIWTFLRDEMSRRRSINDRRKDKEVGTNGH

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1105/tpc.13.4.979; 10.1038/35048500; 10.1111/tpj.13415; 10.1126/science.1088305; 10.1186/1471-2164-10-200

RefSeq

NP_564698.1 [Q8RXR2-1]; NP_849813.1 [Q8RXR2-2]